Be a Step Ahead of Lung Cancer 

When you’re at risk for lung cancer, early detection matters. LEAP is a simple blood test that can help find lung cancer before symptoms appear—giving you and your doctor more time, more options, and greater peace of mind. Diagnosing lung cancer early can significantly improve outcomes, with 5-year survival rates exceeding 70%. LEAP offers a proactive, accessible way to support earlier diagnosis and guide timely next steps in care.

LEAP test box beside a test tube containing a blood sample, labeled 'LEAP' and 'Lung Enzyme Activity Protocol'.

LEAP for the Early Detection of Lung Cancer

The LEAP blood test detects specific enzyme patterns linked to lung cancer through a simple blood test.

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An Abnormal result indicates that additional testing, like a chest CT, may be recommended by your healthcare provider.

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Talk to your doctor to see if LEAP is right for you,

Currently, 76% of lung cancer diagnoses occur in advanced stages when it has already spread and chances of a cure are reduced. Earlier detection is crucial for successful treatment of lung cancer. The LEAP test can be used to trigger additional screening and earlier treatment.

Who is the LEAP Test For?

LEAP is recommended for individuals at higher risk for lung cancer, based on guidelines from the U.S. Preventive Services Task Force (USPSTF), including:

Adults
50–80
years old

Individuals with a
20 pack-year
smoking history

Current smokers
or those that quit within the
past 15 years

Note: LEAP is not intended for individuals who have been diagnosed with lung cancer or are currently in treatment.

How LEAP Works

LEAP measures the activity of specific enzymes in your blood. These enzyme patterns can signal whether you may be at increased risk for lung cancer—even before any symptoms appear.

Your result will be reported as either:

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Normal: The enzyme pattern does not indicate lung cancer. Your provider may recommend continuing routine screening.

Abnormal: The enzyme pattern is similar to that seen in individuals with lung cancer. This is not a diagnosis, but follow-up testing such as imaging may be recommended by your doctor.

Why Consider LEAP?

LEAP supports early detection efforts by identifying molecular signals in your blood—potentially before lung cancer would show up on a scan.

LEAP is clinically validated
with 99.8% negative predictive value

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    Simple

    Requires only a standard blood draw

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    Safe

    No radiation, no imaging, no prep

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    Fast

    Receive results in just a few days

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    Proactive

    May trigger earlier follow-up care

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    Trusted

    Backed by clinical research and performed in a CLIA-certified lab

How to Get the LEAP Test

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    Talk to your provider

    Your doctor can help determine if LEAP is appropriate for you. Contact Ease Healthcare for a listing of providers.

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    Complete your blood draw

    Testing is done either in your provider’s office or through a participating Ease Healthcare partner.

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    Review your results

    You’ll receive your results within a few days, and your doctor will explain what they mean and recommend next steps if needed.

More Information About LEAP

Is the LEAP test covered by insurance?

Most health insurance plans do not currently cover the cost of the LEAP test. However, you may be able to use pre-tax dollars from a Flexible Spending Account (FSA) or Health Savings Account (HSA). Check with your plan administrator or insurance provider to confirm eligibility.

Is LEAP FDA-approved?

No. LEAP is a laboratory-developed test (LDT) that has not been cleared or approved by the FDA. It is performed by a CLIA-certified and CAP-accredited lab authorized to conduct high-complexity clinical testing.

Can LEAP give false results?

Yes. Like all medical tests, LEAP may produce false-positive or false-negative results.

  • A false-positive result means the test indicates a possible issue when no cancer is present.

  • A false-negative result means the test may miss the presence of cancer.

Test results should always be interpreted by a healthcare provider in the context of your medical history and current symptoms.

LEAP RESOURCES FOR PATIENTS

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